What is Poxet 30mg used for?
Poxet 30mg (dapoxetine 30mg) are used to treat premature ejaculation (PE), which is one of the most common causes of sexual dysfunction in men. It is defined as early ejaculation with minimal sexual stimulation before or soon after penetration, and can cause distress and problems with relationships. Poxet is used to improve control over ejaculation and increase the time interval before ejaculation occurs during intercourse, for men with persistent or recurrent PE.
How does Poxet work?
Poxet tablets 30mg contain dapoxetine 30mg, a selective serotonin reuptake inhibitor (SSRI) that is used specifically for premature ejaculation (PE), as it has a rapid onset of action, with maximum effect within 1-2 hours and a short half-life, which means that it is rapidly eliminated from the body within 24 hours. Ejaculation is a reflex that is mediated by the sympathetic nervous system. When sexual stimulation has reached a certain threshold, sensory nerve cells in the spinal cord are activated and nerve impulses are sent to the brain, which then send messages back to motor neurones controlling the muscles in the penis that contract to effect ejaculation. The ejaculation reflex is thought to be mediated by serotonin, a specific brain chemical or neurotransmitter that is involved is transmitting nerve signals, which enables brain cells to communicate. Low levels of serotonin in certain areas of the brain are thought to be responsible for causing PE. Dapoxetine in Poxet blocks the reuptake of serotonin from the synapse, which is the gap between nerve cells across which chemical messages are sent from one nerve cell to another. If the re-uptake of serotonin by the first nerve cell (pre-synaptic) is blocked, this means that there is more serotonin remaining for the receiving nerve cell (post-synaptic), which allows nerve cells to communicate with each other for longer. This action of dapoxetine in Poxet 30 helps prolong the ability to maintain sexual activity without premature ejaculation and maintain control over ejaculation for longer.
What does Poxet contain?
Poxet tablets 30mg contain active ingredient dapoxetine, a selective serotonin reuptake inhibitor (SSRI) that is used to treat and prevent persistent or recurrent premature ejaculation (PE). They also contain : lactose, cellulose-microcrystalline, croscarmellose sodium, silica-colloidal anhydrous, magnesium stearate, hypromellose, titanium dioxide, iron oxide black, iron oxide yellow.
What are the side effects of Poxet?
The most commonly reported side effects when taking Poxet tablets30mg include,
Gastrointestinal upset (nausea, diarrhoea, dry mouth, abdominal discomfort),
Increased blood pressure,
What medications interact with Poxet?
Several medications interact with Poxet tablets 30mg and should either not be taken while you are taking Poxet or only after discussion and instruction from your doctor:
Drugs that cause a serious reaction with Poxet: monoamine oxidase inhibitors for depression, thioridazine for schizophrenia, the anticoagulant warfarin increases risk of bleeding, NSAIDs like aspirin or ibuprofen St. JohnÂ´s Wort, migraine medicines like sumatriptan, the analgesic tramadol, SSRI antidepressants like paroxetine or citalopram, SNRI antidepressants like venlafaxine, lithium for mood disorders,
Drugs that affect Poxet: thioridazine for schizophrenia, antifungals like ketoconazole, antibiotics like erythromycin, HIV treatments like ritonavir and atazanavir, calcium channel blockers like diltiazem for hypertension
How should Poxet be taken?
You should take your Poxet tablets 30mg swallowed whole with a glass of water with or without food. You should take your Poxet tablet 1-3 hours before planned sexual activity. You should not take more than one tablet in 24 hours and avoid alcohol.
How should Poxet be stored?
You should store your Poxet tablets below 25Â°C in a cool dry place.
Poxet Tablets – Dosage
It is taken by mouth, in tablet form. The dose is usually 60 mg but may be reduced for certain patients. Consult your doctor for exact dosing instructions. Dosage depends mainly on your body weight.
Take the medicine as required, about 1 to 3 hours before sexual activity. The maximum recommended dose is once every 24 hours.
Take the Poxet tablet whole with a glass of water.
Drug Class and Mechanism
Dapoxetine, the active ingredient present in Poxet Tablets is a short-acting selective serotonin reuptake inhibitor (SSRI) marketed for the treatment of premature ejaculation in men. Delaying male climax is a well-known effect of certain antidepressants. The time to maximal plasma concentration is only 1 hour. The initial elimination half-life is 1.2 hours, and the plasma concentration at 24 hours is < 5% of the maximal concentration. These properties allow for dapoxetine to be delivered as an on-demand preparation.
Poxet (Generic Dapoxetine) has the ability to lengthen the time between sexual arousal and climax.
The effect of dapoxetine can last as long as 15 hours.
Poxet (Generic Dapoxetine) is the only drug with regulatory approval for the indication of premature ejaculation (PE).